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Leveraging the latest macroeconomic data, on-chain behavior, and regulatory developments, this article provides a comprehensive breakdown of the Latin American stablecoin market’s evolution. It explores how stablecoins have progressed from instruments of survival amid currency collapse and banking exclusion to serving as the backbone of Web3 financial infrastructure, evidenced by $1.5 trillion in on-chain transaction volume. The article also uncovers the alpha opportunities behind the emergence of Crypto Neobanks.